Extending Donor Organ Preservation Time

Outcome/Accomplishment

The National Science Foundation (NSF) Engineering Research Center (ERC) for Advanced Technologies for the Preservation of Biological Systems (ATP-Bio), based at the University of Minnesota, and several of its member partners were highlighted in a June 2026 Nature Biotechnology feature article examining the rapid progress being made in cryobiology and organ preservation. The article, “Next-gen cryo promises transplant surgeons more time,” explores emerging technologies that could extend the preservation time of donor organs from hours to days, and ultimately enable long-term organ banking. In particular it features NSF ATP-Bio’s groundbreaking recent progress in biopreservation and transplant innovation.

Impact/Benefits

Sub-zero technologies that reduce ice damage in organs will extend donor-graft shelf life, offering transplant centers more time to match recipients and save lives. ATP-Bio’s achievements in this field are shaping the future of translational research in transplantation and biomedicine and will have significant impact on cryopreservation science and organ preservation.

Explanation/Background

The feature article recognizes the contributions of ATP-Bio researchers and partner/member organizations, including the University of Minnesota, Massachusetts General Hospital, Texas A&M University, Maximize Bio, BioChoric, and Until Labs, who are advancing innovations in subzero preservation, cryoprotectants, vitrification, and organ rewarming technologies.

Nature Biotechnology also notes the growing national investment in cryobiology and highlights the role of NSF ERCs in fostering collaboration among academic, industry, and clinical partners to accelerate innovation and translation. The article underscores the importance of ATP-Bio’s work in developing technologies that preserve, store, transport, and distribute biological systems—advances that could fundamentally change how organs, tissues, cells, and other biological materials are used in medicine.

“Recognition in Nature Biotechnology reflects the remarkable progress being made across the cryobiology community and the power of collaborative research to address one of medicine’s most significant challenges,” said Dr. John Bischof, ATP-Bio Center Director. “Our vision is to make biological preservation a transformative platform technology that expands access to transplantation and improves patient outcomes.”

Image
Credit:
Robert Kneschke/Alamy

Location

Minneapolis, Minnesota

e-mail

atp-bio@umn.edu

Start Year

Biotechnology and Healthcare

Biotechnology and Health Care Icon
Biotechnology and Health Care Icon

Biotechnology and Healthcare

Lead Institution

University of Minnesota

Core Partners

Massachusetts General Hospital, University of California, Berkeley, University of California, Riverside
Image
Credit:
Robert Kneschke/Alamy

Outcome/Accomplishment

The National Science Foundation (NSF) Engineering Research Center (ERC) for Advanced Technologies for the Preservation of Biological Systems (ATP-Bio), based at the University of Minnesota, and several of its member partners were highlighted in a June 2026 Nature Biotechnology feature article examining the rapid progress being made in cryobiology and organ preservation. The article, “Next-gen cryo promises transplant surgeons more time,” explores emerging technologies that could extend the preservation time of donor organs from hours to days, and ultimately enable long-term organ banking. In particular it features NSF ATP-Bio’s groundbreaking recent progress in biopreservation and transplant innovation.

Location

Minneapolis, Minnesota

e-mail

atp-bio@umn.edu

Start Year

Biotechnology and Healthcare

Biotechnology and Health Care Icon
Biotechnology and Health Care Icon

Biotechnology and Healthcare

Lead Institution

University of Minnesota

Core Partners

Massachusetts General Hospital, University of California, Berkeley, University of California, Riverside

Impact/benefits

Sub-zero technologies that reduce ice damage in organs will extend donor-graft shelf life, offering transplant centers more time to match recipients and save lives. ATP-Bio’s achievements in this field are shaping the future of translational research in transplantation and biomedicine and will have significant impact on cryopreservation science and organ preservation.

Explanation/Background

The feature article recognizes the contributions of ATP-Bio researchers and partner/member organizations, including the University of Minnesota, Massachusetts General Hospital, Texas A&M University, Maximize Bio, BioChoric, and Until Labs, who are advancing innovations in subzero preservation, cryoprotectants, vitrification, and organ rewarming technologies.

Nature Biotechnology also notes the growing national investment in cryobiology and highlights the role of NSF ERCs in fostering collaboration among academic, industry, and clinical partners to accelerate innovation and translation. The article underscores the importance of ATP-Bio’s work in developing technologies that preserve, store, transport, and distribute biological systems—advances that could fundamentally change how organs, tissues, cells, and other biological materials are used in medicine.

“Recognition in Nature Biotechnology reflects the remarkable progress being made across the cryobiology community and the power of collaborative research to address one of medicine’s most significant challenges,” said Dr. John Bischof, ATP-Bio Center Director. “Our vision is to make biological preservation a transformative platform technology that expands access to transplantation and improves patient outcomes.”